兰索拉唑联合抗生素治疗酒精型消化溃疡的临床效果

Investigation on the clinical effect of lansoprazole combined with antibiotics in the treatment of alcoholic peptic ulcer

目的:探讨兰索拉唑联合抗生素治疗酒精型消化溃疡的疗效。方法:收治酒精型消化溃疡患者72例,按随机数字表法分为对照组和观察组各36例,对照组给予奥美拉唑联合抗生素治疗,观察组给予兰索拉唑联合抗生素治疗。结果:观察组总有效率高于对照组(P<0.05);观察组不良反应发生率、复发率低于对照组(P<0.05)。结论:兰索拉唑联合抗生素治疗酒精型消化溃疡疗效较好,有效根除Hp感染,不良反应少,且复发率低。

Objective:To evaluate the clinical efficacy of lansoprazole combined with antibiotics in the treatment of alcoholic peptic ulcer.Methods:72 patients with alcoholic peptic ulcer.They were randomly divided into the control group and the observation group with 36 cases in each.Patients in the control group were given omeprazole combined with antibiotic treatment,while in the observation group were given lansoprazole combined with antibiotic treatment.Results:The total effective rate of the observation group were higher than that of the control group(P<0.05).The incidence of adverse reactions and recurrence rate in the observation group were lower than those in the control group(P<0.05).Conclusion:Lansoprazole combined with antibiotics inthe treatment of alcoholic peptic ulcer has good curative effect.It can eradicate Hp infection effectively,with less adverse reaction and low recurrence rate.