阿卡波糖独特的制作工艺和流程

Uniqueness and Specificity of Manufacture Technology and Process of Acarbose

阿卡波糖是德国拜耳公司治疗糖尿病的原研药,其悠久的历史、独特的制作工艺与流程确保了其临床疗效的稳定性。近几年阿卡波糖在中国的临床应用研究再次证实其满意的疗效和安全,奠定其在指南中的一线用药地位。本文就从阿卡波糖的发现、工艺、应用回顾其历史,全面展示从实验室、工厂走向临床的44年历程。

Acarboseis a drug to treat diabetes,was provided by the originator company--Bayer HealthCare Pharmaceuticals(Germany).It haslong history,unique manufacture technology and specific process,Which ensure clinical therapeutic stability.In recent years,clinic application trialsof acarbose in China have provided robust evidences for its satisfactory efficacy and safety,contributing its first-line status in guideline.This articlereviews the history of its discovery,manufacture technology and process,comprehensively demonstrating the44years-lasting pathway from bench,factory building to bedside.