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替格瑞洛在急性冠脉综合征介入治疗中的临床价值分析 被引量:1

Clinical value of ticagrelor in the treatment of acute coronary syndrome
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摘要 目的:探讨替格瑞洛在急性冠脉综合征介入治疗中的效果。方法:收治急性冠脉综合征患者98例,分为试验组与对照组,各49例。试验组患者接受替格瑞洛治疗,对照组患者接受氯吡格雷治疗。结果:试验组患者抑制血小板聚集效果明显优于对照组,且试验组心脑血管事件发生率明显低于对照组。结论:将替格瑞洛应用于冠脉综合征的临床治疗过程中,能够加速抗血小板聚集,且极大降低心脑血管事件的发生概率。 Objective:To investigate the effect of ticagrelor in interventional treatment of acute coronary syndrome.Methods:98patients with ACS were selected.They were divided into the experimental group and the control group with49cases in each.Theexperimental group received ticagrelor treatment.Patients in the control group received clopidogrel treatment.Results:Inhibition ofplatelet aggregation in the experimental group was significantly better than in the control group,and the incidence of adversecardiovascular events in the experimental group was significantly lower than that in the control group.Conclusion:Application ofticagrelor in the treatment of coronary syndrome can accelerate the role of anti platelet aggregation,and greatly reduce theincidence of adverse cardiovascular events.
作者 张建华 李辉 Zhang Jianhua;Li Hui(Development of Internal Medicine,Economic and Technological Zone Hospital of Handan City,Hebei Province 056000;Department of Internal Medicine-Cardiovascular,East Area of Handan Central Hospital,Hebei Province 056001)
出处 《中国社区医师》 2017年第12期30-30,32,共2页 Chinese Community Doctors
关键词 替格瑞洛 氯吡格雷 急性冠脉综合征 血小板聚集率 不良心血管事件 Ticagrelor Clopidogrel Acute coronary syndrome Platelet aggregation rate Adverse cardiovascular events
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  • 1ZHANG Xiao-lin,HAN Ya-Ling,ZHANG Bao-Hai,KANG Jian,YAN Cheng-Hui (Department of Cardiology,Cardiovascular Institute of PLA, Shenyang Northern Hospital.Shenyang 110031,China).Interleukin-8 gene polymorphism is associated with acute coronary syndrome in a Han Chinese population[J].岭南心血管病杂志,2011,17(S1):151-151. 被引量:11
  • 2柯元南,陈纪林.不稳定性心绞痛和非ST段抬高心肌梗死诊断与治疗指南[J].中华心血管病杂志,2007,35(4):295-304. 被引量:2153
  • 3Sangu P, Ranasinghe I, Aliprandi B,et al. Trends and predictors of rehospitalisation following an acute coronary syndrome: report from the Australian and New Zealand population of the Global Registry of Acute Coronary Events (GRACE) [J].Heart, 2012,98 (23) : 1728-1731.
  • 4Hasan A,Hakan O,Ali K,et al. The effect of high-dose clopidogrel treatment in patients with clopidogrel resistance(The EFFICIENT Trial)[J]. Int J Cardiol, 2012,157(3 ) : 374-380.
  • 5Lars W,Stefan J,Robert F,et al. Effect of CYP2C19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: a genetic substudy ofthePLATO trial[Jl.Lancet,2010,376(9749): 1320-1328.
  • 6Lars W, Richard C, Andrzej B, et al. Ticagrelor versus clopidogrel in patients with acute coronary syndromes[J]. N Engl J Med,2009, 361( 11 ) : 1045-1057.
  • 7Antman M,Hand M,Armstrong W,et al. 2007 focused update of the ACC/AHA 2004 guidelines for the management of patients with ST-elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines[J]. J Am Coll Cardiol, 2008,51 (2) : 210-247.
  • 8Pena A, Collet P, Hulot S, et al. Can we override clopidogrel re- sistance[J].Circulation, 2009,119( 21 ) : 2854-2857.
  • 9Wang X D,Zhang D F,Liu X B ,et al. Modified clopidogrel loading dose according to platelet reactivity monitoring in patients carrying ABCB1 variant alleles in patients with clopidogrel resistance[J].Eur J Intern Med, 2012,23 ( 1 ) :48-53.
  • 10齐新,刘克强,王敏,尹皓烨,赵春杰,李松松.冠心病患者血小板聚集功能与炎症因子关系的研究[J].中国循环杂志,2009,24(3):178-181. 被引量:30

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