拜糖平与二甲双胍对2型糖尿病患者降糖临床效果及不良作用

Clinical effect of acarbose and metformin on hypoglycemic effect and adverse effects of patients with type 2 diabetes

目的:研究拜糖平与二甲双胍在2型糖尿病患者中的治疗效果以及不良反应。方法:收治2型糖尿病患者58例,随机分为研究组和对照组各29例。对照组给予二甲双胍治疗,研究组给予拜糖平治疗,比较两组患者治疗前后的血糖值变化情况以及不良反应。结果:治疗后,两组患者的血糖值均有所改善,研究组的餐后血糖值下降情况明显优于对照组,对照组的空腹血糖值下降程度低于研究组(P<0.05);两组患者的不良反应发生率差异无统计学意义(P>0.05)。结论:在2型糖尿病患者的治疗中,拜糖平与二甲双胍均有显著的降糖作用,且不良反应较少。

Objective:To study the treatment effect and adverse reaction of acarbose and metformin in patients with type2diabetes.Methods:58patients with type2diabetes were selected.They were randomly divided into the study group and the controlgroup with29cases in each.The control group was given metformin treatment,and the study group was given acarbose treatment.The blood glucose changes before and after treatment and adverse reactions were compared between groups.Results:Aftertreatment,the blood glucose values of two groups were improved,the postprandial blood glucose of the study group decreasedsignificantly better than that of the control group,and the fasting blood glucose of the control group decreased lower than that ofthe study group(P<0.05).The difference of adverse reaction rates of the two groups was not statistically significant(P>0.05).Conclusion:In the treatment of patients with type2diabetes,the acarbose and metformin have significant hypoglycemic effect,andthe adverse reaction is less.