4393名大学新生入学体检丙氨酸氨基转移酶检测结果分析

Analysis of Test Results of Serum Alanine Aminotransferase (ALT) in 4 393 University Freshmen

目的探讨大学新生入学体检丙氨酸氨基转移酶(ALT)异常率及影响ALT异常的相关因素。方法对2015年4 393名大学新生进行入学健康体检,分析血清ALT异常检出率及影响ALT异常的因素。结果4 393名大学生的血清ALT异常检出率为6.65%,其中男性为11.06%,女性为2.78%,男性显著高于女性(χ~2=120.801,P<0.01);本省新生ALT异常检出为6.08%,外省新生为8.62%,外省新生ALT异常检出率高于本省新生(χ~2=7.982,P<0.01)。分析影响ALT异常因素中超重肥胖比例最高(56.51%),其次为高尿酸血症(44.18%),第三为乙型肝炎表面抗原(HBsAg)阳性(10.62%)。结论大学生的ALT异常与性别、体重指数、生源地域、高尿酸血症、乙型肝炎病毒阳性等因素密切相关。

Objective To study the abnormal rate and influential factors of serum alanine aminotransferase(ALT)results in university freshmen.Methods The author conducted physical examination for4393university students enrolled in2015,also calculated their serum ALT abnormal rate and revealed its influential factors.Results The gross abnormal detection rate was6.65%,which was11.06%for men and2.78%for women,respectively.The former was substantially higher than latter(χ2=120.801,P<0.01).The abnormal detection rate was6.08%for local students and8.62%for students from other provinces.In other words,the former was apparently lower than the latter(χ2=7.982,P<0.01).According to the analysis results,the most prominent contributing factor was obesity(56.51%),which was followed by hyperuricemia(44.18%).The third factor was the HBsAg-positive(10.62%).Conclusion The ALT abnormal rate is related to gender,body mass index,area of origin students,hyperuricemia and hepatitis B infection.