12种婴幼儿食品接触热塑性弹性体制品中潜在迁移物的分析

Analysis of Potential Migrants in Twelve Infant Food Contact Thermoplastic Elastomer Products

利用固相微萃取-气相色谱-质谱联用技术对12种婴幼儿食品接触热塑性弹性体制品中挥发性及半挥发性的潜在迁移物进行定性及半定量分析。样品通过DVB/CAR/PDMS、CAR/PDMS、Polyacrylate三个固相微萃取纤维头进行非目标物的提取,气相色谱-质谱联用进行分离鉴定,检出的68种化合物结合标准品和保留指数进行确证,单点内标法进行半定量分析。根据检出率、保留指数及含量进行步分3级筛选,最后提出32种需要重点关注的化合物,包括硅氧烷类、芳香烃类、烷烃类、醛类、酯类及酚类等。该研究为后续的特定物质的迁移实验、暴露评估等研究提供了研究思路和科学依据。

In this study,qualitative and semi-quantitative analysis of volatile and semi-volatile potential migrants in12infant food contact thermoplastic elastomer(TPE)products were carried out by solid phase microextraction and gas chromatography-mass spectrometry(SPME-GC-MS).Non-target compounds were extracted by divinylbenzene/carboxen/polydimethylsiloxane(DVB/CAR/PDMS),CAR/PDMS and polyacrylate fibers,and separated and identified by GC-MS.A total of68compounds were detected and further confirmed by comparison of retention indices with those of reference standards,and the semi-quantitative analysis of these compounds was carried out by single point internal standard method.All the compounds were filtered in sequence by three-step screening based on their detection rates,retention indices and contents.Finally,a total of32compounds,including siloxanes,aromatics,alkanes,aldehydes,esters and phenols,were regarded as being of concern.This study may provide a scientific basis for future studies on the migration and exposure assessment of specific substances.