复方丹参对早发型重度子痫前期患者围产结局的影响

Efficacy of Fufang Danshen on perinatal outcome of early severe preeclampsia patients

目的:研究复方丹参对早发型重度子痫前期患者围产结局的影响。方法:选取我院2013年1月-2014年1月62例早发型重度子痫前期患者为研究对象,运用随机数表法分为观察组和对照组。对照组采用常规治疗,观察组在常规治疗的基础上注射复方丹参注射液。比较两组脐动脉S/D比值及羊水指数(AFI)、1min新生儿评分(Apgar评分)、自然分娩方式及围产结局。结果:脐动脉S/D比值治疗前高于治疗后,AFI低于治疗后,两组比较差异有统计学意义(P<0.05)。治疗后观察组脐动脉S/D比值低于对照组,AFI高于对照组,两组比较差异有统计学意义(P<0.05)。两组1min Apgar评分≥7的比例分别为64.5%、83.8%,两组比较差异无统计学意义(P>0.05)。两组自然阴道分娩率分别为35.4%、45.1%,两组分娩方式比较差异无统计学意义(P>0.05)。观察组在新生儿质量、妊娠终止周期上高于对照组,两组比较差异有统计学意义(P<0.05),两组产后2h出血量比较差异无统计学意义(P>0.05)。结论:复方丹参有助于提高对早发型重度子痫前期的治疗效果,并且能够减少并发症,改善围产结局,值得临床应用和推广。

Objective:To study the effect of Fufang Danshen on perinatal outcome in patients with severe preeclampsia.Methods:62patients were randomly divided into the observation group and control group by random digital table method.The control group was treated by conventional therapy.The observation group was injected with the Fufang Danshen injection more.Results:The ratio of umbilical artery S/D was higher than before treatment.AFI was lower than that after treatment(P<0.05).The ratio of umbilical artery S/D in the observation group was lower than the control group.AFI was higher than that in the control group(P<0.05).The proportion of Apgar score≥7in two groups was64.5%and83.8%,respectively.There was no significant difference between two groups(P>0.05).There were no significant differences in the mode of delivery between two groups(P>0.05).The neonatal quality,pregnancy termination cycle in the observation group is higher than the control group(P>0.05).There was no significant difference in blood loss between two groups(P>0.05).Conclusion:Fufang Danshen can improve the therapeutic effect on early-onset severe preeclampsia,and reduce the complication and improve the perinatal outcome,is worthy of clinical application and promotion.