摘要
Aspergillus. niger is a common fungus with strong UV tolerance, primarily due to the melanin layer adhering tothe conidial cell wall[1]. Melanins are dark-brown to black pigments found in animals, plants, and microorganisms.Their functions of enhancing the survival and competitive abilities of species in certain environments attractsresearchers. Efficient inhibitors of melanin synthesis are important for melanin biosynthetic pathway study. It isbelieved that melanin in Apergillus niger is synthesized via 1,8-dihydroxynaphtalene (1,8-DHN) pathway[2]. However,tricyclazole, the specific inhibitor of DHN melanin, cannot inhibit Aspergillus niger melanin synthesis[3]. It isimportant for us to find effective inhibitors of Aspergillus niger melanin synthesis. This study aimed to investigatethe inhibitors reported of melanin synthesis, and find the most effective one for Aspergillus niger melanin.
