摘要
Based on the periodic synchrotron-based beam delivery,a bio-audiovisual feedback breathing guidance technique has been developed to mitigate the interplay between target motion and dynamic beam delivery for ion beam therapy,in which variable beam extraction and generation of individualized breathing guidance curve are two key factors.Shown in Fig.1 is the schematic diagram of the breathing guidance technique.Through the simulations with 15 healthy volunteers for the breathing guidance technique,we found not only the treatment efficiency of synchrotron-based pulsed ion beam could be increased effectively,but also the residual movement of respiration during gating window could be reduced.