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3-57 Protective Effect of Diallyl Disulfide on Carbon Ion Irradiation-induced Cell Death in Mouse Testis via p73 Signaling Pathway, But Not p53

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摘要 Diallyl Disulfide (DADS) is the main organosulfur component of garlic and it is known for multiple pharmacologicalactions. Currently, DADS has been well documented to ameliorate the testis injuries caused by X-rayirradiation[1??4]. However, the effect of DADS against heavy-ion-induced testis damage, particularly cell apoptosis,is still largely unknown. In this regard, based on ground experiments at accelerators, this study has been undertakento estimate the protective mechanisms of DADS against carbon ion-induced cell apoptosis at the level ofsignal transduction pathway in mouse testis.
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出处 《IMP & HIRFL Annual Report》 2014年第1期152-152,共1页 中国科学院近代物理研究所和兰州重离子研究装置年报(英文版)
基金 Key Program of National Natural Science Foundation of China (U1432248), National Natural Science Founda-tion of China (11175222, 11205219) , Western Talent Program of Chinese Academy of Sciences (Y260230XB0)
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