细胞DNA定量分析技术在宫颈癌筛查中的应用

Application of cell DNA quantitative analysis technique in cervical cancer screening

目的:探讨细胞DNA定量分析技术在宫颈癌筛查中的应用效果。方法:对2 102例体检妇女进行宫颈癌筛查,分别采用TBS常规液基细胞学和DNA定量分析系统检测诊断,比较诊断结果。结果:对联合常规细胞学和DNA定量分析,能够显著提升检测的敏感度、特异性、阳性预测值和阴性预测值。结论:联合常规细胞学和细胞DNA定量分析技术,可显著提高宫颈癌的检出率。

Objective:To explore the application effect of cell DNA quantitative analysis technique in cervical cancer screening.Methods:2102cases of women were screened for cervical cancer.They were diagnosed using TBS conventional liquid basedcytology and DNA quantitative analysis systems.We compared the diagnostic results.Results:Combined with routine cytology andDNA quantitative analysis,the sensitivity could significantly improve the detection sensitivity,specificity,positive predictive valueand negative predictive value.Conclusion:The detection rate of cervical cancer was significantly increased by combinedconventional cytology and DNA quantitative analysis.