2,2′-联吡啶-4,4′-二丙烯酸的合成

Synthesis of 2,2′-Bipyridine-4,4′-dipropenoic Acid

在保护气和加压的条件下,2,2′-联吡啶-4,4′-二甲酸甲酯和乙酸甲酯在催化剂作用下,得到2,2′-联吡啶-4,4′-二丙烯,并通过熔点和核磁对产物结构进行了表征,并得到最佳工艺条件.

2,2′-bipyridine-4,4′-dipropenoic acid was synthesized from2,2′-bipyridine-4,4′-dicarboxylate and methyl acetate with catalyst under the argon and high pressure.The characterization of structure was confirmed by melt point and1H-NMR,and the optimum conditions was obtained through the further optimization.