A型肉毒毒素联合针刺在脑卒中后中枢性面瘫治疗中的应用

Application of Botulinum Toxin Type A Combined with Acupuncture on Central Facial Paralysis after Stroke

目的:探讨A型肉毒毒素联合针刺法在脑卒中后中枢性面瘫患者的临床应用效果。方法:将120例脑卒中后中枢性面瘫患者随机分为四组,对照组给予常规面部肌肉运动锻炼,观察A组给予A型肉毒毒素注射,观察B组给予针刺疗法,观察C组给予A型肉毒毒素+针刺疗法;干预4周后,评估两组患者的临床效果。结果:三个观察组的治疗有效率、美容满意度均高于对照组,差异有统计学意义(P<0.05);观察C组的治疗有效率、美容满意度高于观察A组、观察B组,差异有统计学意义(P<0.05);在躯体功能(FDIP)及社会生活功能(FDIS)得分上,三个观察组干预后得分高于干预前得分,差异有统计学意义(P<0.05);三个观察组干预后得分高于对照组干预后得分,差异有统计学意义(P<0.05);观察C组干预后得分高于观察A组及观察B组,差异有统计学意义(P<0.05)。结论:A型肉毒毒素联合针刺在脑卒中后中枢性面瘫患者具有较好的临床效果,能够降低面瘫程度,提高美容满意度。

Objective To investigate the clinical effect of botulinum toxin type A combined with acupuncture in patients with central facial paralysis after stroke.Methods120cases of facial paralysis after stroke were randomly divided into four groups,the control group was given routine facial muscle exercise,observation group A treated with botulinum toxin type A injection,the observation group B was given acupuncture therapy,observation group C treated with botulinum toxin typeA and acupuncture therapy.After4weeks of intervention,the clinical outcomes of the two groups were evaluated.Results Three groups of treatment efficiency,beauty and satisfaction were higher than the control group,the difference was statistically significant(P<0.05).Treatment group C efficiency and beauty satisfaction is higher than the observation group A and groupB,the difference was statistically significant(P<0.05).In the physical function(FDIP)and the function of social life(FDIS)score,three groups scored higher than the score before the intervention,the difference was statistically significant(P<0.05).Three observation group after the intervention group scored higher than the score of the control,the difference was statisticallysignificant(P<0.05).Observation group C score higher than intervention observation group A and group B,the difference wasstatistically significant(P<0.05).Conclusion Botulinum toxin type A combined with acupuncture has better clinical effect in patients with central facial paralysis after stroke.