依达拉奉联合舒血宁治疗急性脑梗死临床疗效观察

Observation on clinical curative effect of edaravone combined with Shuxuening in the treatment of acute cerebral infarction

目的分析依达拉奉联合舒血宁治疗急性脑梗死的临床疗效。方法 48例急性脑梗死患者为研究对象,随机分为研究组和对照组,每组24例。对照组患者给予常规治疗,研究组患者在对照组基础上给予依达拉奉联合舒血宁治疗。观察两组患者的临床治疗效果。结果治疗后,研究组患者的治疗总有效率为91.67%,对照组患者的总有效率为66.67%;研究组患者的总有效率明显高于对照组,差异有统计学意义(P<0.05)。治疗前,研究组患者神经功能缺损(NIHSS)评分为(20.15±3.06)分,对照组为(21.11±3.08)分;治疗后,研究组患者NIHSS评分为(9.0±2.06)分,对照组为(12.17±2.54)分;治疗前两组NIHSS评分比较差异无统计学意义(P>0.05);治疗后两组NIHSS评分均低于治疗前,且研究组低于对照组,差异有统计学意义(P<0.05)。结论依达拉奉联合舒血宁能够有效治疗急性脑梗死疾病,改善脑梗死患者的临床症状,对脑梗死患者治疗预后也有一定的改善作用,值得推广使用。

Objective To analyze the clinical curative effect of edaravone combined with Shuxueningin the treatment of acute cerebral infarction.Methods A total of48acute cerebral infarction patients as studysubjects were randomly divided into research group and control group,with24cases.The control group receivedconventional therapy,and the research group received edaravone combined with Shuxuening for treatment on thebasis of the control group.Clinical treatment effect was observed in two groups.Results After treatment,theresearch group had total effective rate as91.67%,while the control group had total effective rate as66.67%.Theresearch group had obviously higher total effective rate than the control group,and the difference had statisticalsignificance(P<0.05).Before treatment,the research group had National Institutes of Health stroke scale(NIHSS)score as(20.15±3.06)points,which was(21.11±3.08)points in the control group.After treatment,the researchgroup had NIHSS score as(9.0±2.06)points,which was(12.17±2.54)points in the control group.Both groupshad no statistically significant difference in NIHSS score before treatment(P>0.05).After treatment,both groupshad lower NIHSS score than that before treatment,and the research group was lower than the control group.Their difference had statistical significance(P<0.05).Conclusion Combination of edaravone and Shuxuening iseffective in treating acute cerebral infarction,and it can improve clinical symptoms of patients.It also has certainimprovement effect for treatment prognosis.So it is worthy of promotion and use.