心境障碍患者生命质量和社会功能状况的病例对照研究

A case-control study on the quality of life and social function among patients with mood disorders

目的分析心境障碍患者生命质量及社会功能特点,为提升患者生命质量和改善其社会功能提供理论依据。方法以2010年厦门市精神疾病流行病学调查中241例心境障碍患者为病例组,按照1∶1的配对病例对照研究方法,在同社区或村选择同性别、同年龄(±3岁)选择对照组。两组人群采用自制一般人口学资料、12项一般健康问卷、简易生命质量量表、功能大体评定量表进行评定,并对两组人群生命质量和社会功能进行比较。结果心境障碍患者生命质量得分低于对照组,差异有统计学意义(t=12.69,P<0.001)。心境障碍患者社会功能得分低于对照组,差异有统计学意义(t=17.77,P<0.001)。两因素方差分析显示,在排除性别、年龄、职业、受教育年限、婚姻状况、医疗来源、居住情况及宗教信仰等因素后,心境障碍患者生命质量及社会功能得分均低于对照组(P<0.001)。结论心境障碍患者生命质量、社会功能低于对照组,应根据不同人群特征制定相应措施提升其生命质量和改善社会功能。

Objective To analyze the characteristics related to quality of life and social function among patients with mood disorders,and it also to provide necessary evidence for policies makers.Methods In our study,241patients with mood disorders diagnosed in mental health epidemiology in2010years,and they were selected and served as case.According the distributions on gender,age(±3years),village or community,241persons without any psychiatric disorders were selected as control,under1∶1paired choice.The demographic data,General Health Questionnaire,Simplify Quality of Life Scale,Global Assessment of Functioning Scale were assessed among two groups,then compared to the quality of life and social function.Results Scores of Quality of life among patients with mood disorders was lower than that of the control group,with statistically significant difference(t=12.69,P<0.001).Scores of social function among patients with mood disorders was lower than that of the control group,with statistically significant difference(t=17.77,P<0.001).The results from the two factors Anova-analysis showed that the scores of the quality of life and social function were lower than the scores of the control group,regardless of gender,age,occupation,education,marital status,medical resource,living status,religious belief.Conclusion Patients with mood disorder had lower scores of quality of life and social function than control group.We should develop measures to improve the life qualify and social functioning according to the different characteristics.