喹诺酮类药物致急性肾衰竭临床分析

Clinical analysis of acute renal failure caused by quinolones

目的:探讨喹诺酮类药物致急性肾衰竭的临床特点以及治疗方法。方法:收治喹诺酮类药物致急性肾衰竭的患者80例,分析临床病例,并根据患者病情特点给予针对性治疗。结果:喹诺酮类药物致急性肾衰竭的病例主要集中在中老年患者中,随着年龄的增长,喹诺酮类药物导致急性肾衰竭的发生概率呈现增加趋势;少尿型急性肾衰竭类型患者预后更佳。结论:喹诺酮类药物的不当使用会损害患者的肾脏,极容易导致急性肾衰竭问题。因此,临床上要注意喹诺酮类药物的合理使用,最大化地减少药物使用中不良反应发生率。

Objective:To investigate the clinical characteristics and treatment of acute renal failure caused by quinolones.Methods:80patients with acute renal failure caused by quinolones were selected.We analyzed the clinical cases,according to the characteristics of the patients to give targeted treatment.Results:The cases of acute renal failure caused by quinolones were mainlyin the middle and old aged patients,with the increase of age.The incidence of acute renal failure caused by quinolones increased.Patients with oliguria acute renal failure type have better prognosis.Conclusion:Improper use of quinolones can damage the kidneys of patients,which can easily lead to acute renal failure.Therefore,it is necessary to pay attention to the rational use of quinolones in clinic,and reduce the incidence of adverse drug reactions.