不规则抗体筛查在安全有效输血中的意义

The significance of irregular antibody screening in safe and effective blood transfusion

目的:探讨不规则抗体筛查在安全有效输血中的意义。方法:收治需要输血及手术备血的患者31 186例,对全部患者的血标本实施不规则抗体筛查,分析引起抗体筛查阳性的因素。结果:女性阳性率0.29%,明显高于男性的0.18%(P<0.05);此外,又以既往有输血史及妊娠史的患者的阳性率居多。结论:在输血之前实施不规则抗体筛查,重点对有妊娠史及多次输血史的患者进行筛查,并输注完全配合型的血液,可以有效避免或减少发生溶血性输血反应的风险,确保输血的有效性及安全性。

Objective:To explore the significance of irregular antibody screening in safe and effective blood transfusion.Methods:31186patients who required blood transfusion and surgical preparation of blood were selected.The blood samples from all patients were detected by irregular antibody screening.We analyzed the factors that cause positive antibody screening.Results:The positive rate of female was0.29%,which was higher than0.18%of male(P<0.05).In addition,the majority of patients with positive rate were those who had history of blood transfusion and pregnancy.Conclusion:Performing irregular antibody screening prior to transfusion,focusing on screening for patients with a history of pregnancy and multiple transfusions,and with the infusion of fully matched blood can effectively avoid or reduce the risk of hemolytic transfusion reaction,to ensure the effectiveness and safety of blood transfusion.