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白内障患者血中同型半胱氨酸的浓度观

Plasma homocysteine levels in patients with cataract
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摘要 目的:探讨同型半胱氨酸与白内障的关系。方法:收治白内障手术患者115例,测定血浆中同型半胱氨酸(Hcy)浓度。结果:随着年龄的增长,HHcy血症越多,患白内障的风险越大。结论:HHcy是致白内障的一个因素。 Objective:To investigate the relationship between homocysteine and cataract.Methods:115patients with cataract surgery were enrolled in the study,and then measured plasma homocysteine(Hcy)levels.Results:With the increase of age,the more HHcy,and the risk of cataract greater.Conclusion:HHcy is a pathogenic factors of cataract.
作者 窦红威 Dou Hongwei(Department of Clinical Laboratory,Oilfield General Hospital of Henan Province 163316)
出处 《中国社区医师》 2017年第15期112-112,115,共2页 Chinese Community Doctors
关键词 白内障 同型半胱氨酸 浓度 Cataract Homocysteine Concentration
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  • 1Jakubowski H. The pathophysiological hypothesis of homo- cysteine thiolactone-mediated vascular disease. J Physiol Pharmacol, 2008,59 : 155- 167.
  • 2Jakubowski H. Molecular basis of homocysteine toxicity in humans. Cell Mol Life Sci, 2004, 61 : 470-487.
  • 3Jakubowski H. The molecular basis of homocysteine thiolac- tone-mediated vascular disease. Clin Chem Lab Med, 2007, 45 : 1704 - 1716.
  • 4Jakubowski H. Homocysteine-thiolactone and S-nitroso-ho- mocysteine mediate incorporation of homocysteine into pro- tein in humans. Clin Chem Lab Med, 2003, 41 : 1462 -1466.
  • 5Wang W, Rusin O, Xu X, et al. Detection of homocysteine and cysteine. J Am Chem Soc, 2005, 127 : 15949 15958.
  • 6Wang W, Escobedo JO, Lawrence CM, et al. Direct detec- tion of homocysteine. J Am Chem Soc, 2004, 126 : 3400- 3401.
  • 7Sibrian-Vazquez M, Escobedo JO, Lim S, et al. Homocys- tamides promote free-radical and oxidative damage to proreins. Proc Natl Acad Sci USA, 2009, 107 : 551 -554.
  • 8Paoli P, Sbrana F, Tiribilli B, et al. Protein N-homocystei- nylation induces the formation of toxic amyloid-like protofi- brils. J Mol Biol, 2010, 400 : 889 -907.
  • 9Schoenich C. Mechanisms of protein damage induced by cysteine thiyl radical formation. Chem Res Toxicol, 2008, 21 : 1175 - 1179.
  • 10Yang X, Gao Y, Zhou J, et al. Plasma homocysteine thio- lactone adducts associated with risk of coronary heart dis- ease. Clin Chim Acta, 2006, 364 : 230 -234.

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