老年高血压合并早期肾损害应用氨氯地平和替米沙坦联合治疗的疗效分析

Therapeutic effect of amlodipine combined with telmisartan in the treatment of elderly patients with hypertensive and early renal damage

目的:探讨老年高血压合并早期肾损害患者应用氨氯地平和替米沙坦联合治疗的临床疗效。方法:收治老年高血压早期肾损害患者106例,随机分为观察组与对照组,对照组采用氨氯地平治疗,观察组采用氨氯地平联合替米沙坦治疗,比较两组治疗效果。结果:观察组临床疗效和mALB改善情况明显优于对照组(P<0.05);观察组不良反应情况明显少于对照组。结论:老年高血压合并早期肾损害患者应用氨氯地平和替米沙坦联合治疗的临床疗效显著。

Objective:To explore the therapeutic effect of amlodipine combined with telmisartan in the treatment of elderlypatients with hypertension and early renal damage.Methods:106cases of elderly patients with hypertension and early renaldamage were selected.They were randomly divided into the observation group and the control group.The control group was treatedwith amlodipine.The observation group was treated with amlodipine combined with telmisartan.We compared the therapeuticeffect of two groups.Results:In the observation group,the clinical efficacy and improvement of mALB were significantly better thanthose of the control group(P<0.05).The adverse reactions in the observation group were significantly less than those in the controlgroup.Conclusion:The therapeutic effect of amlodipine combined with telmisartan in the treatment of elderly patients withhypertension and early renal damage was significant.