甲强龙冲击治疗婴儿痉挛症的疗效评价

Evaluation on the curative effect of methylprednisolone pulse therapy in infantile spasms

目的:探讨甲强龙冲击治疗婴儿痉挛症的疗效。方法:收治婴儿痉挛症患儿19例,首选甲强龙治疗作为观察组。另外选取同时期非首选甲强龙治疗的21例婴儿痉挛症患儿作为对照组。结果:观察组患儿在治疗第1周、第2周时的完全缓解率与治疗总有效率均高于对照组(P<0.05)。结论:甲强龙冲击治疗婴儿痉挛症的疗效显著,早期应用效果更佳。

Objective:To evaluate the clinical efficacy of methylprednisolone therapy on infantile spasms.Methods:19childrenwith infantile spasms were selected,then they were given methylprednisolone as the preferred treatment.In additions,21cases ofinfantile spasms were selected at the same time as the control group,and methylprednisolone was non preferred treatment in thecontrol group.Results:The complete remission rate and total effective rate of the observation group were higher than those of thecontrol group at the first and second weeks of the treatment(P<0.05).Conclusion:Methylprednisolone has significant therapeuticeffect on infantile spasms,and applicating the sooner the better.