重组人脑利钠肽治疗老年急性左心衰竭的短期疗效与安全性研究

Short term efficacy and safety of recombinant human brain natriuretic peptide in the treatment of elderly patients with acute left heart failure

目的:探讨重组人脑利钠肽治疗老年急性左心衰竭的短期疗效与安全性。方法:收治老年急性左心衰竭患者96例,随机分为常规组和干预组,常规组采用常规治疗,干预组在常规组基础上加重组人脑利钠肽,比较两组治疗效果。结果:干预组治疗总有效率、24 h尿量、左心射血分数、脑钠肽改善幅度明显优于常规组(P<0.05)。结论:重组人脑利钠肽治疗老年急性左心衰竭的短期疗效与安全性高。

Objective:To explore the short term efficacy and safety of recombinant human brain natriuretic peptide in thetreatment of elderly patients with acute left heart failure.Methods:96elderly patients with acute left heart failure were selected.They were randomly divided into the routine group and the intervention group.The routine group were treated by routine treatment.The intervention group added recombinant human brain natriuretic peptide on the basis of the routine group.We compared thetherapeutic effect of two groups.Results:In the intervention group,the total effective rate,24hours urine volume,left ventricularejection fraction and improvement range of brain natriuretic peptide were significantly better than the control group(P<0.05).Conclusion:The short term efficacy and safety of recombinant human brain natriuretic peptide in the treatment of elderly patientswith acute left heart failure were high.