期刊文献+

磷酸西格列汀治疗2型糖尿病35例临床分析 被引量:2

A clinical analysis of treating 35 cases of type 2 diabetes mellitus with sigmatidine phosphate
下载PDF
导出
摘要 目的:探究磷酸西格列汀治疗2型糖尿病患者的临床疗效情况。方法:选取35例在我院2016年1月-2016年6月接受治疗的2型糖尿病患者做研究,随机分为对照组、观察组,对照组17例患者,观察组18例患者。对照组给予胰岛素注射治疗,观察组给予磷酸西格列汀治疗。对比两组患者的临床疗效、胆固醇、糖化血红蛋白和C肽的情况。结果:观察组患者总有效率为94.44%,胆固醇及糖化血红蛋白的恢复状况较好,C肽的活性更大,观察组优越性高(P<0.05)。结论:磷酸西格列汀对于2型糖尿病的临床治疗效果显著。 Objective:To investigate the clinical efficacy of sigmatidine phosphate on type2diabetes mellitus.Methods:35patients were randomly divided into control group(n=17)and observation group(n=18).Control group took insulin injection therapy,observation group took sigmatidine phosphate treatment.Results:The total effective rate was94.44%in the observation group,the recoveryof cholesterol and glycated hemoglobin was better,the activity of C peptide was higher,and the superiority of the observation group washigher(P<0.05).Conclusion:Sigmatadine phosphate has a significant effect on type2diabetes mellitus.
出处 《中医临床研究》 2017年第12期44-46,共3页 Clinical Journal Of Chinese Medicine
关键词 磷酸西格列汀 糖尿病 临床分析 Sigmatidine phosphate Diabetes Clinical analysis
  • 相关文献

参考文献7

二级参考文献37

  • 1杜强,王艳军,杨生,等.磷酸西格列汀对2型糖尿病患者Apelin水平的影响[J].中华临床医师杂志(电子版)2013;7(22):10021-10024.
  • 2de Valk HW.DPP-4 inhibitors and combined treatment in type 2 diabetes:re-evaluation of clinical success and safe- ty[J].Rev Diabet Stud,2007,4(3): 126-133.
  • 3Chia CW,Egan JM.Incretin-based therapies in type 2 dia- betes mellitus [J].Clin Endocrinol Metab, 2008,93 (10) : 3703-3716.
  • 4Drucker DJ.Dipeptidyl peptidase-4 inhibition and the treat- ment of type 2 diabetes:preelinical biology and mecha- nisms of action[J].Diabetes Care,2007,30(6) : 1335-1343.
  • 5Tian L,Gao J,Hao J,Zhang Y,et a/.Reversal of new-on- set diabetes through modulating inflammation and stimu- lating beta-cell replication in nonobese diabetic mice by a dipeptidyl peptidase 1V inhibitor[J].Endocrinology,2010, 151 (7) : 3049-3060.
  • 6Herman-Hermen W,Johnson J,Teng R,et a/.Efficaey and safety of initial combination therapy with sitagliptin and metformin in patients with type 2 diabetes: a 54-week study[J].Curr Med Res Opin, 2009,25 (3) : 569-583.
  • 7Herman DW,Johnson J, TeugR,et aLEfficacy and safety of sitagliptin and metformin as initial combination therapy and as monotherapy over 2 years in patients with type 2 diabetes[J].Diabetes Obes Metab, 2010,12(5) :442-451.
  • 8Vilsll T,Rosenstock J,Yki-J rvinen H,et aLEfficacy and safety of sitagliptin when added to insulin therapy in pa- tients with type 2 diabetes [J].Diabetes Obes Metab, 2010, 12(2) : 167-177.
  • 9Migoya EM,Stevens CH,Bergman AJ,et al. Effect of mod- erate hepatic insufficiency on the pharmacokinetics of phar- macokinetics of sitagIiptin[J].Can J Clin Pharmacol, 2009, 16(1) : 165-170.
  • 10Raz I, Chen Y, Wu M,et a/.Efficacy and safety of Sitagliptin added to ongoing metformin therapy in patients with type 2 diabetes [J]. Curr Med Res Opin,2008,24(2):537-550.

共引文献16

同被引文献11

引证文献2

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部