清热、化瘀、补益序贯疗法熏洗促进肛瘘术后创面修复的临床研究

Clinical effect of TCM therapies on postoperative anal fistula wound healing

目的:评价清热、化瘀、补益序贯疗法促进肛瘘术后创面修复的临床疗效。方法:采用随机对照临床试验研究方法,将符合纳入标准的100例肛瘘术后患者随机分为两组,每组50例,对照组予高锰酸钾熏洗,治疗组根据创面分析采用中医辨证处方治疗方案(早期清热、中期化瘀、后期补益法)序贯疗法熏洗。观察并记录两组患者术后症状如创面疼痛、水肿、渗液情况及肉芽生长情况,同时记录创面愈合天数。结果:两组患者术后第3、7、14天观察组与对照组相比在术后创面疼痛、渗液、水肿及肉芽组织形态方面有统计学差异(P<0.05);观察组与对照组相比显著缩短愈合天数、提高术后愈合率(P<0.05);两组术后14天疗效评定有差异,观察组疗效优于对照组。结论:清热化瘀补益序贯疗法熏洗能明显缩短肛瘘术后创面疼痛、水肿、渗液时间,促进肉茅组织生长,提高创面愈合率,促进创面愈合。

Objectives:To observe clinical effect with Fumigation and Washing of Qingre Huayu Buyi for postoperative analfistula wound healing.Methods:100anal fistula surgery cases were randomly divided into two groups,the observation group(QingrehuayuFang group)50cases,the control group(potassium permanganate group)50cases.Results:Comparing the average disappear time of postoperativesymptoms and the days of wound healing between the two groups,pain effusion edema and granulation in the observationgroup significantly was reduced more than the control group(P<0.05);Fumigation and Washing with Qingrehuayu Fang acceleratedwound healing and shorten healing time,post-operative healing rate in the observation group remarkably was improved(P<0.01);14days after surgery,the post-operative evaluation has a difference between the two groups,clinical effects in the observation group wasbetter than the control group.Conclusion:Fumigation and Washing with Qingrehuayu Fang can improve post-operative symptoms(thepain effusion edema and granulation of postoperative anal fistula)and promote wound healing rate of postoperative anal fistula