生脉注射液联合丹参多酚酸盐注射液治疗冠心病慢性心力衰竭的疗效分析

Clinical efficacy of the Shengmai injection plus salvianolate injection on chronic heart failure in coronary heart disease

目的:分析生脉注射液联合丹参多酚酸盐注射液对冠心病慢性心力衰竭(CHF)的疗效。方法:择取的冠心病CHF患者88例全部为我院心血管内科2015年1月-2016年11月间收治,将其随机分为两组各44例,对照组给予常规西医内科治疗,治疗组在其基础上给予生脉注射液联合丹参多酚酸盐注射液治疗,比较两组的临床症状、心功能及血清学指标的变化。结果:干预后,治疗组胸闷、气短、心悸等临床症状评分明显低于对照组,LVEF、CO、CI心功能指标明显高于对照组,血清hs-CRP、TNF-α及IL-6水平明显低于对照组(P均<0.05)。结论:生脉注射液联合丹参多酚酸盐注射液可缓解冠心病CHF患者的临床症状,促进心功能及炎性反应的好转,值得临床推广应用。

Objective:To analyze clinical efficacy of the Shengmai injection plus salvianolate injection on chronic heart failure incoronary heart disease.Methods:88patients were divided into2groups,44cases for each.The control group was given the conventionalwestern medicine;and the treatment group was given the Shengmai injection plus salvianolate injection more.Clinical symptoms,cardiacfunction and serum markers in two groups were compared.Results:After treatment,chest tightness,shortness of breath,palpitations andother clinical symptoms score in the treatment group were significantly lower than the control group;the heart function indexes of LVEF,CO and CI in the treatment group were significantly higher than those in the control group;and the levels of serum hs-CRP,TNF-αandIL-6in the treatment group were significantly lower than those in the control group(P<0.05).Conclusion:The Shengmai injection plussalvianolate injection on chronic heart failure in coronary heart disease shows a good effect,and is worthy of promotion.