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硫辛酸对早期糖尿病足患者氧化应激与炎症反应的影响 被引量:7

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摘要 目的分析研究硫辛酸对早期糖尿病足患者氧化应激与炎症反应的影响。方法抽取糖尿病足的66例患者进行分组研究,随机分为观察组与对照组,各33例。对照组采用常规治疗方法,观察组在对照组治疗基础上加用硫辛酸,对比观察治疗前后两组患者氧化应激指标及炎症因子变化情况。结果经治疗观察组TAOC、SOD、MDA水平分别为(8.04±0.13)IU/m L、(81.02±3.10)IU/m L、(4.04±0.13)umol/L,hs-CRP、TNF-α、IL-6水平分别为(4.12±0.14)ng/L、(35.12±1.29)ng/L、(9.14±0.66)ng/L,对照组TAOC、SOD、MDA水平分别为(6.41±0.14)IU/m L、(70.12±2.21)IU/m L、(6.76±0.15)umol/L,hs-CRP、TNF-α、IL-6水平分别为(6.23±0.23)ng/L、(47.15±1.56)ng/L、(13.76±0.65)ng/L,组间比较差异有统计学意义(P<0.05)。结论采用硫辛酸治疗早期糖尿病足患者可有效缓解炎症反应及氧化应激反应,具有一定临床价值。
出处 《当代医学》 2017年第18期97-98,共2页 Contemporary Medicine
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