他巴唑药物治疗过程中引发甲状腺功能减低的观察

The observation of about hypothyroidism triggered by Thiamazole Tablets

目的:探讨弥漫性甲状腺功能亢进病人用他巴唑药物治疗过程中出现甲状腺功能减低的因素及如何防治等。方法:选择2013年-2015年间新发病的甲亢病人进行观察。结果:治疗过程中发生甲低因素与甲亢发病年龄、性别及甲亢病情等关系不大,而与他巴唑药物治疗总量有关。结论:他巴唑药物在治疗甲亢病人过程中出现甲低时,迅速减少剂量即可;或在减少他巴唑剂量的同时加用少量甲状腺素。

Objective:To evaluate the factors which lead to hypothyroidism In Thiamazole Tablets treatment fordiffuse hyperthyroldism patients and the way of prevention and cure,ect.Methods:Observe the newly diagnosedhyperthyroid patients during the period between2013and2015.Result:The factors which lead to hypothyroidismhave little relationship with the age,sex and the state of hyperthyroidism patients,but are related to the total metThiamazole dosage.Conclusion:It is effective to immediately reduce Thiamazole dosage when hypothyroidism occursin the treatment for hyperthyroidism patients,or to add small amount of thyroxine,meanwhile,reduce Thiamazoledosage.