分析下肢慢性创伤性骨髓炎患者创面细菌培养分布情况

An analysis of bacterial culture in patients with chronic traumatic osteomyelitis of lower extremities

目的:探讨下肢慢性创伤性骨髓炎患者创面细菌性培养分布,为临床提供依据。方法:选取2012年1月-2015年10月我院慢性骨髓炎患者90例为研究对象,回顾性调查分析创面分泌物细菌培养标本,抗生素疗程>1周。结果:创面细菌培养阳性患者64例,分离病原菌112株,G^-菌72株(64.3%)、G^+菌40株(35.7%);药敏结果显示,G^+菌对常规青霉素类耐药、碳青霉烯类耐药菌株较少,未出现对万古霉素耐药菌株;G-菌对头孢菌素类、青霉素类药物耐药,对头孢哌酮-舒巴坦类药物不耐药。结论:监测慢性创伤性骨髓炎患者创面病原菌可为提升抗生素合理性提供有价值的参考依据。

Objective:To explore the distribution of bacterial culture in patients with chronic traumatic osteomyelitis of lowerextremities.Methods:90cases were selected as study subjects.Bacterial culture of wound secretion specimens were analyzed.Antibioticswere used for more than1week.Results:64cases were positive bacterial culture in wound.112strains of pathogens were isolated;72strains(64.3%)were G-bacteria and40(35.7%)were G+bacteria.The results showed that G+bacteria were resistant to conventionalpenicillin.Mildewen resistant strains are fewer,with no vancomycin-resistant strains;G-bacteria has resistance on cephalosporins,penicillinsdrug,with no intolerancece on foperazone-sulbactam drug.Conclusion:Surveillance of pathogens in patients with chronic traumaticosteomyelitis can provide valuable reference for improving the rationality of antibiotics.