重组组织型纤溶酶原激活剂溶栓后应用疏血通注射液在脑梗死急性期的疗效观察

Observation on treating acute cerebral infarction with the Shuxuetong injection plus reconstructive tissue plasminogen activator

目的:观察重组组织型纤溶酶原激活剂(Rt-PA)溶栓后应用疏血通注射液治疗早期急性脑梗死的临床疗效。方法:回顾性分析2013年12月-2016年1月鹤壁市淇县中医院收治的120例急性脑梗死患者,根据是否实施疏血通注射液治疗分为观察组(在按照指南规范常规西医治疗的基础上应用疏血通注射液)和对照组(按照指南规范常规治疗),每组60例。对比分析两组患者治疗后的脑梗死灶体积、NIHSS和GOS评分、血管再通率、临床疗效及并发症发生情况。结果:观察组患者脑梗死灶体积明显小于对照组,差异有统计学意义(P<0.05);观察组患者NIHSS评分和GOS评分明显低于对照组,差异有统计学意义(P<0.05);治疗后观察组患者脑温明显低于对照组,差异有统计学意义(P<0.05);观察组总有效率明显高于对照组(P<0.05)。结论:Rt-PA溶栓后应用疏血通注射液治疗早期急性脑梗死具有显著的临床疗效,能够缩小梗死面积,有效降低患者神经功能的缺损,促进肢体功能的恢复,具有重要的临床意义和研究价值。

Objective:To observe efficacy of the Shuxuetong injection plus Rt-PA on acute cerebral infarction.Methods:120caseswere divided into the observation group(given the Shuxuetong injection plus conventional medicine)and control group(conventionaltreatment),60patients in each group.Results:Cerebral infarct volume was significantly smaller in the observation group(P<0.05);NIHSSscore and GOS score were significantly lower in the observation group(P<0.05);after treatment,brain temperature was lower in theobservation group(P<0.05);the total efficiency was significantly higher in the observation group(P<005).Conclusion:Rt-PA thrombolysisplus the Shuxuetong injection on early acute cerebral infarction was significantly effective,by reducing infarct size,effectively reducing thedefects of nerve function,and promoting the recovery of limb function,and has important clinical significance and research value.