低浓度罗哌卡因联合舒芬太尼椎管内阻滞用于分娩镇痛的效果分析

Effect analysis of low concentration ropivacaine combined with sufentanil spinal block for labor analgesia

目的探讨低浓度罗哌卡因联合舒芬太尼椎管内阻滞用于分娩镇痛的效果。方法 160例镇痛分娩产妇,按照随机数字表法分为A组和B组,各80例。A组采用低浓度罗哌卡因联合舒芬太尼行连续硬膜外阻滞镇痛分娩,B组采用低浓度罗哌卡因联合舒芬太尼行腰硬联合阻滞镇痛分娩。选取同期80例未行镇痛分娩的产妇作为C组。比较三组分娩情况。结果 A组和B组的镇痛15 min、镇痛30 min、宫口全开时视觉模拟评分法(VAS)评分均低于C组,B组镇痛15 min、镇痛30 min的VAS评分低于A组,差异具有统计学意义(P<0.05)。A组的镇痛起效时间为(195.44±34.77)s,B组的镇痛起效时间为(43.26±9.72)s,B组镇痛起效时间短于A组,差异具有统计学意义(t=37.701,P<0.05)。三组产妇镇痛后30 min的Bromage评分、产程时间、分娩方式以及新生儿Apgar评分比较,差异无统计学意义(P>0.05)。结论低浓度罗哌卡因联合舒芬太尼椎管内阻滞用于分娩镇痛的效果显著,安全性高,值得进一步在临床上推广应用。

Objective To explore the effect of low concentration ropivacaine combined with sufentanilspinal block for labor analgesia.Methods A total of160analgesia delivery puerpera were divided by randomnumber table method into group A and group B,with80cases in each group.Group A received low concentrationropivacaine combined with sufentanil for continuous epidural block analgesia delivery,and group B received lowconcentration ropivacaine combined with sufentanil spinal block for analgesia delivery.Concurrent80puerperawithout analgesia delivery were taken as group C.Delivery situation was compared in three groups.ResultsGroup A and group B had lower visual analogue scale(VAS)score after15,30min of analgesia and at the timeof cottage full open than group C.Group B had lower VAS score after15,30min of analgesia than group A.Theirdifference had statistical significance(P<0.05).Group A had analgesic onset time as(195.44±34.77)s,whilegroup B had analgesic onset time as(43.26±9.72)s.Group B had shorter analgesic onset time than group A,and the difference had statistical significance(t=37.701,P<0.05).Three groups had no statistically significantdifference in Bromage score after30min of analgesia,duration of labor,mode of delivery and neonatal Apgarscore(P>0.05).Conclusion Combination of low concentration ropivacaine and sufentanil spinal block showssignificant effect for labor analgesia with high safety,and it is worthy of further clinical promotion and application.