维持性血液透析患者矿物质和骨代谢紊乱回顾性分析

Retrospective analysis of mineral and bone metabolic disorders in maintenance hemodialysis patients

目的对临床进行维持性血液透析患者矿物质和骨代谢紊乱（MBD）情况进行回顾性分析。方法选取我院2015年1月至2016年6月期间收治的维持性血液透析患者125例MBD情况进行回顾性分析，对透析质量进行回顾评价。结果进行维持性血液透析治疗的患者主要存在实验室检查异常、骨骼异常及影像学异常。而血钙、血iPTH、透析龄、年龄、透析次数是影响血磷变化的独立因素（P＜0.05）。结论对于临床进行维持性血液透析治疗的患者，应加强对患者钙磷水平控制，减少矿物质和骨代谢紊乱发生情况，从而降低致残率和致死率，提高患者生存质量。

Objective Retrospective analysis of mineral and bone metabolic disorder(MBD)in maintenance hemodialysis patients.Methods125cases of maintenance hemodialysis patients were selected from January2015to June2016in our hospital,which were retrospective analysed of mineral and bone metabolic disorder(MBD)and were retrospective assessed of dialysis quality.Results There are laboratory examination abnormalities,skeletal abnormalities and imaging abnormalities in these maintenance hemodialysis patients.Serum calcium,blood iPTH,age of dialysis,age and dialysis times were independent factors of blood phosphorus change(P<0.05).Conciusions For maintenance hemodialysis patients,we should strengthen the control of calcium and phosphorus levels and reduce the occurrence of mineral and reduce the incidence rate of bone metabolic disorders,accordingly to reduce the disability rate and the fatality rate,and to improve the quality of patients'life.