麻醉诱导后不同维持麻醉方法对老年肿瘤患者手术后认知功能的影响

Influence of different methods of maintenance anesthesia after anesthesia induction on postoperative cognitive function in elderly patients with tumor

目的:探讨麻醉诱导后不同维持麻醉方法对老年肿瘤患者手术后认知功能的影响。方法:收治外科手术肿瘤患者108例(60岁以上),分为A组和B组。A组采用持续静脉泵注丙泊酚维持麻醉,B组采用静脉泵注丙泊酚+吸入异氟醚维持麻醉,比较两组苏醒情况和认知功能。结果:两组术后苏醒时间、拔管时间、话语时间和认知功能障碍发生率比较,差异无统计学意义(P>0.05)。A组认知功能恢复正常时间明显低于B组(P<0.05)。结论:静脉麻醉维持对老年肿瘤患者术后认知功能的影响小于静吸复合麻醉维持。

Objective:To explore the influence of different methods of maintenance anesthesia after anesthesia induction onpostoperative cognitive function in elderly patients with tumor.Methods:108patients(over60years of age)with tumor and surgicaloperation were selected.They were divided into the A group and the B group.The A group received continuous intravenouspumping propofol to maintain anesthesia.The B group received intravenous pumping propofol combined with inhaled isoflurane tomaintain anesthesia.We compared recovery and cognitive function between groups.Results:The postoperative recovery time,extubation time,speech time and incidence of cognitive impairment were not significantly different between groups(P>0.05).Inthe A group,the recovery time of cognitive function was significantly lower than the B group(P<0.05).Conclusion:The influence oftotal intravenous anesthesia maintenance on postoperative cognitive function in elderly patients with tumor was less than thecombined intravenous and inhalation anesthesia maintenance.