血管三维结构定量特征指标研究进展

Advances of Three Dimensional Blood Vessel Quantitative Feature

血管的形态与功能的病理性改变是多种疾病的诱因,同时在特定的病理状态下,血管也会发生特定的改变。由于血管与疾病的密切联系,通过对血管的定量分析可以对某些疾病进行早期预测和临床诊断。二维血管定量分析常常会受到结构重叠的影响,因此三维血管定量分析结果更加准确。近年来,随着三维成像技术的不断发展,三维血管定量分析的研究具有重要应用价值。为此,系统总结了血管图像获取到三维血管结构生成相关技术,并按照三维血管节段、血管分支与血管网络三个层次整理相关定量表征指标,为影像组学中血管结构的特征提取提供基础。

Pathological changes of vascular morphology and function could result in a variety of diseases;meanwhile,the blood vessels might change in a particular disease in a certain manner.Due to the close relationship between blood vessels and diseases,quantitative analyses of blood vessels are of significance in early prediction and diagnosis of certain diseases.The accuracy of two-dimensional vascular quantitative analysis is often affected by the structural overlap during imaging;hence it is more accurate to perform such analysis on three-dimensional(3d)models.With the development of3d imaging technology in recent years,3d vascular quantitative analysis becomes more and more important.This paper reviewed the relevant technology from the acquisition of vessel images to the formation of3d vascular structure,and we summarized relevant quantitative indicators at the levels of vascular segment,vascular branch and vascular network,which could provide a basis for feature extraction of vascular structures in radiomics.