2014年河南省水源性高碘地区重点人群尿碘监测及相关因素分析

Analysis of iodine nutritional status among vulnerable population in high water iodine areas of Henan Province in 2014

目的了解河南省水源性高碘地区重点人群碘营养水平,为制定水源性高碘地区干预策略提供依据。方法在商丘、新乡、濮阳、开封4个省辖市各选择一个高碘县,在水碘>150μg/L地区的医院、妇幼保健院、计生部门等收集新婚育龄妇女、孕妇、哺乳期妇女、0~2岁婴幼儿4类人群的尿样,检测尿碘含量。每个县区每类人群调查100名。结果新婚育龄妇女、孕妇、哺乳期妇女、0~2岁婴幼儿的尿碘中位数分别是287.4、278.4、248.6、292.5μg/L,其中,>300的比例分别为48.4%、45.9%、38.3%、49.0%。孕妇妊娠早、中、晚期的尿碘中位数分别为274.7、260.9、286.2μg/L,差异无统计学意义。1岁以内母乳喂养婴儿尿碘中位数是318.4μg/L,显著高于人工(256.0μg/L)和混合喂养(237.5μg/L)的婴儿(P<0.05)。结论河南省水源性高碘地区重点人群的尿碘水平总体偏高,并且新婚育龄妇女和孕妇有碘过量的风险。

Objective To assess iodine nutritional status among vulnerable population in high water iodine areas,and provide the basis for making prophylaxis strategies of iodine excess.Methods One county with high water iodine was selected from Shangqiu,Xinxiang,Puyang,Kaifeng city.In each selected county,100reproductive-age,pregnant and lactating women and infants<2years were selected from hospital,maternal and childcare hospital,and family planning organizations in the areas where water iodine was above150μg/L.Results The median urinary iodine concentrations(mUICs)of reproductive-age,pregnant and lactating women and infants<2years were287.4,278.4,248.6and292.5μg/L,respectively.The proportion of urinary iodine>300μg/L were48.4%,45.9%,38.3%and49.0%,respectively.The mUICs of pregnant women in the first,second,and third trimester were274.7,260.9,286.2μg/L,respectively.No significant difference was found.The mUIC of breast-fed infants<1year(318.4μg/L)was significantly greater than formula-fed(256.0μg/L)and mixed-fed(237.5μg/L)infants(P<0.05).Conclusion Iodine status of the vulnerable populations in high water iodine areas of Henan Province was on the high level as a whole in Henan province.Reproductive-age and pregnant women were at the risk of iodine excess.