噻托溴铵联合舒利迭治疗重度与极重度慢性阻塞性肺疾病的效果评价

Evaluation of the effect of tiotropium bromide combined with seretide in the treatment of severe and very severe chronic obstructive pulmonary disease

目的:评价噻托溴铵联合舒利迭治疗重度与极重度慢性阻塞性肺疾病的效果。方法:收治老年慢性阻塞性肺疾病患者70例,分为重度组34例和极重度组36例,观察和评价两组的治疗效果。结果:极重度组患者的临床疗效76.47%,重度组患者的临床疗效73.53%,两组数据差异不具统计学意义(P>0.05);两组患者的潮气量(VT)、补吸气量(IRV)、深吸气量(IC)、肺活量(VC)、肺总量(TLC)差异不具有统计学意义(P>0.05)。结论:噻托溴铵联合舒利迭治疗重度与极重度慢性阻塞性肺疾病的效果确切,具有较高的肺功能恢复率,且两组患者的治疗效果差异无统计学意义。

Objective:To evaluate the effect of tiotropium bromide combined with seretide in the treatment of severe and verysevere chronic obstructive pulmonary disease.Methods:70elderly patients with chronic obstructive pulmonary disease wereselected.There were34cases in the severe treatment group and36cases in the very severe treatment group.The clinical effects oftwo groups were observed and evaluated.Results:The clinical efficacy of the patients in the very severe group was76.47%and theclinical efficacy in the severe group was73.53%.The difference between groups was not statistically significant,and there was nostatistical significance(P>0.05).The tidal volume(VT),inspiratory aspiration volume(IRV),deep inspiratory volume(IC),vitalcapacity(VC)and total lung volume(TLC)of the two groups were not significant,with no statistically significant(P>0.05).Conclusion:Tiotropium bromide combined with seretide in the treatment of severe and very severe chronic obstructive pulmonary disease hassignificant effect.The rate of recovery of lung function is high,and the difference between the two groups is not obvious.