良性发作性位置性眩晕患者治疗后复发的影响因素研究

Influencing factors of post-treatment recurrence in patients with benign paroxysmal positional vertigo

目的探讨良性发作性位置性眩晕患者治疗后复发的相关因素,以期能为后期治疗提供依据。方法回顾性分析2011年5月-2014年3月眉山市中医医院门诊收治的479例良性发作性位置性眩晕患者的临床资料,依据患者复发情况分为复发组和无复发组。统计良性发作性位置性眩晕患者治疗后复发情况,包括复发率、复发时间和复发次数。比较两组患者的临床资料,并进行单因素分析和多因素Logistic回归分析。结果良性发作性位置性眩晕患者479例,其中101例(21.09%)复发,复发时间:1~6个月41例(40.59%),6~12个月48例(47.52%),12个月以上11例(10.89%);复发次数:1次54例(53.47%),2次39例(38.61%),3次及以上8例(7.92%)。单因素分析结果显示,两组患者在年龄、受累半规管、病程、复位次数、发作次数、外伤史、合并高血脂、糖尿病方面差异有统计学意义(P<0.05)。对单因素分析中差异有统计学意义的因素进行多因素Logistic回归分析,结果显示病程>7 d、复位次数、外伤史、合并高血脂、糖尿病是良性发作性位置性眩晕治疗后复发的独立危险因素(P<0.05)。结论病程、复位次数、外伤史、合并高血脂、糖尿病是良性发作性位置性眩晕治疗后复发的独立危险因素,医护人员应加强临床护理,降低复发率。

Objective To investigate the factors associated with post-treatment recurrence in patients with benignparoxysmal positional vertigo,in order to provide basis for further treatment.Methods The clinical data of479patients with benign paroxysmal positional vertigo treated in our hospital from May2011to March2014wereretrospectively analyzed.The patients were divided into recurrence group and non-recurrence group.Recurrentsituation of the patients including recurrence rate,recurrence time and recurrence times was statistically analyzed.The clinical data of the two groups were compared,and the univariate analysis and multivariate logistic regressionanalysis were performed.Results Of the479patients with benign paroxysmal positional vertigo,101cases(21.09%)relapsed.The time of recurrence was1-6months in41cases(40.59%),6-12months in48cases(47.52%),morethan12months in11cases(10.89%).As to the recurrence times,54cases(53.47%)recurred once,39cases(38.61%)twice,8cases(7.92%)3times and more.Univariate analysis showed that there were significant differencesin age,affected semicircular canal,course of disease,number of reset,attack frequency,history of trauma,combinedhyperlipidemia and diabetes between the two groups of patients(P<0.05).Multivariate logistic regression analysisshowed that duration of disease>7d,number of times of reduction,history of trauma,and hyperlipidemia anddiabetes mellitus were the independent risk factors for the recurrence of benign paroxysmal positional vertigo(P<0.05).Conclusions Course of disease,number of times of reduction,history of trauma,high blood lipids,anddiabetes are the independent risk factors for recurrence of benign paroxysmal positional vertigo.Medical workersshould strengthen clinical nursing and reduce the recurrence rate.Keywords:benign paroxysmal positional vertigo;recurrence;multivariate