大肠杆菌与肺炎克雷白杆菌的耐药性分析

Analysis of drug resistance of escherichia coli and klebsiella pneumoniae

目的:探讨大肠杆菌和肺炎克雷白杆菌的耐药特点,指导临床合理用药。方法:收集317株大肠杆菌与80株肺炎克雷白杆菌,进行药敏试验。结果:大肠埃希菌和肺炎克雷白杆菌对阿米卡星的耐药率最高,对厄他培南和亚胺培南的耐药率最低;ICU和泌尿外科大肠杆菌和肺炎克雷白杆菌的耐药率比其他科室高,妇科和儿科肺炎克雷白杆菌的耐药率比其他科室低。结论:细菌的耐药检测以科室为单位进行统计更具有指导意义,临床要根据药敏试验结果选择合适的抗菌药物。

Objective:To investigate the resistance characteristics of escherichia coli and klebsiella pneumoniae,and to guiderational use of drugs in clinic.Methods:We collected317strains of escherichia coli and80strains of klebsiella pneumoniae,andcarried out drug sensitivity test.Results:The resistance rate of escherichia coli and klebsiella pneumoniae for amikacin was thehighest,and the resistance rate was the lowest for ertapenem and imipenem.Compared with other departments,the resistance ratesof escherichia coli and klebsiella pneumoniae in ICU and department of urology were higher,and the resistance rates ofescherichia coli and klebsiella pneumoniae in gynaecology and pediatrics were lower.Conclusion:The detection of bacterialresistance of taking department as unit was more instructive,and the appropriate antibiotics should be selected according to theresult of susceptibility test.