补肺汤化裁对慢性阻塞性肺疾病稳定期(肺脾肾虚、痰瘀互结证)肺功能及血气影响

Effects of the Bufei decoction on pulmonary function and Xueqi of patients with chronic obstructive pulmonary disease at stable stage

目的:探讨补肺汤化裁对慢性阻塞性肺疾病稳定期(肺脾肾虚、痰瘀互结证)肺功能及血气的影响。方法:将60例慢性阻塞性肺疾病稳定期(肺脾肾虚、痰瘀互结证)患者随机分为治疗组和对照组各30例。两组均接受GOLD推荐的规范治疗。对照组在基础治疗上予噻托溴铵粉雾剂18μg吸入,每日1次。治疗组在对照组治疗基础上加用补肺汤化裁治疗。两组疗程为6个月。观察两组治疗前后肺功能、血气、6min步行距离变化情况。结果:治疗后,治疗组FEV_1、FEV_1/FVC显著高于对照组(P<0.05);治疗组PaO_2提高,PaCO_2下降显著优于对照组(P<0.01);治疗组6MWD明显优于对照组(P<0.01)。结论:补肺汤化裁能够改善慢性阻塞性肺疾病稳定期(肺脾肾虚、痰瘀互结证)肺功能和血气状态,提高患者运动耐力。

Objective:To investigate effects of the Bufei decoction on pulmonary function and Xueqi of patients with chronicobstructive pulmonary disease at stable stage(the Feipi Shenxu,Tanyu Hujie type).Methods:60cases were randomly divided into thetreatment group and control group,30cases in each.Both groups received regulatory treatment recommended by GOLD.The controlgroup was given tiotropium bromide powder18μg inhalation,once daily;the treatment group was treated with the Bufei decoction more,for6months.The pulmonary function,Xueqi and6min walking distance were observed.Results:After treatment,the levels of FEV1andFEV1/FVC in the treatment group were significantly higher than those in the control group(P<0.05).PaO2was increased and PaCO2wasdecreased in the treatment group,and significantly better than those in the treatment group(P<0.01);6MWD in the treatment group wassignificantly better than that in the control group(P<0.01).Conclusion:The Bufei decoction can improve the pulmonary function,bloodgas and the athletic endurance.