益心康泰胶囊联合曲美他嗪治疗不稳定型心绞痛的临床研究

Clinical observation on treating unstable angina with the Yixin Kangtai capsules plus trimetazidine

目的:分析不稳定型心绞痛应用益心康泰胶囊与曲美他嗪联合治疗效果与安全性。方法:资料选取2015年6月-2016年6月于我院治疗的122例UAP患者进行回顾,依据治疗方法设对照组(66例)和研究组(56例),前者予常规治疗,后者在此基础上予益心康泰胶囊与曲美他嗪联合治疗,观察两组治疗前后心绞痛及不良反应情况。结果:治疗后,两组心绞痛持续时间与发作次数均减少,但研究组心绞痛持续时间与发作次数少于对照组,比较差异均具有统计学意义(P<0.05)。结论:UAP应用益心康泰胶囊与曲美他嗪联合治疗可减少心绞痛发生次数,无明显不良反应,安全性较高。

Objective:To analyze the efficacy and safety of the Yixin Kangtai capsule with trimetazidine on unstable angina pectoris.Methods:122patients were divided into the treatment group and control group.The treatment group was treated with the Yixin Kangtaicapsule with trimetazidine;the control group was given conventional treatment.Results:After treatment,the time and duration of anginapectoris were decreased;and those were lower in the study group(P<0.05).Conclusion:The Yixin Kangtai capsule with trimetazidine onunstable angina pectoris was effective,by reducing the number of angina pectoris,with no obvious adverse reaction and higher safety.