瑜伽运动对乳腺癌患者化疗期癌因性疲乏及生存质量的影响

Effects of Yoga on cancer-related fatigue and quality of life in breast cancer patients with chemotherapy

目的探讨瑜伽运动干预对乳腺癌化疗患者癌因性疲乏及生存质量的影响。方法 100例乳腺癌患者随机分为实验组和对照组,各50例。化疗期间,对照组给予常规护理,实验组在对照组基础上予以瑜伽运动干预。采用癌症疲乏量表(CFS)、焦虑自评量表(SAS)、抑郁自评量表(SDS)、乳腺癌生存质量测定量表(FACT-B)测评2组术后第2次化疗前和第4、6次化疗结束后的癌因性疲乏、焦虑抑郁情绪及生存质量情况。结果第4、6次化疗后实验组CFS各维度评分、SAS和SDS评分较第2次化疗前均降低,且低于同期对照组评分(P<0.05);重复测量方差分析显示2组生理状况、乳腺癌附加关注评分及FACT-B总分的干预因素与时间因素存在交互作用(P<0.05)。结论瑜伽治疗可有效改善乳腺癌化疗患者躯体疲乏、认知疲乏,缓解患者的焦虑、抑郁情绪,一定程度上提高乳腺癌化疗患者的生存质量。

Objective To investigate the Effects of Yoga on cancer-related fatigue and qualityof life in breast cancer patients with chemotherapy.Methods Totally100breast cancer patientswith chemotherapy were randomly divided into the study group and control group,with50casesin each group.Patients in both two groups were given routine nursing treatment,and the yoga exercisewas carried out in the study group three times a week for1h until the patient was discharged.The Cancer Fatigue Scale(CFS),Self-rating anxiety scale(SAS),Self-rating depressionscale(SDS),Functional Assessment of Cancer Therapy-Breast(FACT-B,V4.0)were usedto evaluated in the2nd,4th and6th chemotherapy.Results The score of CFS,SAS and SDSwere decreased in both two groups after4th and6th chemotherapy compared with those after2ndchemotherapy,and were lower in the study group than those in the control group(P<0.05).Repeatedmeasures analysis of variance showed an interaction between intervention factor and timefactor in physiological condition and mammary cancer supplementary part and overall score ofFACT-B(P<0.05).Conclusion Application of yoga treatment can effectively relieve the physicalfatigue and cognitive fatigue,ease the patient's anxiety and depression,and improve the qualityof life of breast cancer patients.