甲泼尼龙联合阿奇霉素治疗小儿难治性支原体肺炎的疗效与安全性分析

Analysis of the efficacy and safety of methylprednisolone combined with azithromycin in treatment of children with refractory mycoplasma pneumonia

目的:研究、分析甲泼尼龙联合阿奇霉素治疗小儿难治性支原体肺炎的疗效与安全性。方法:收治难治性支原体肺炎患儿98例,平分两组。对照组患儿实施阿奇霉素治疗,研究组患儿联合运用甲泼尼龙和阿奇霉素进行治疗,对比两组患儿的疗效和安全性。结果:研究组患儿的总有效率95.92%,高于对照组的83.67%(P<0.05);研究组患儿的体温恢复时间(6.9±1.5)d,明显短于对照组的(10.7±2.2)d(P<0.05)。结论:甲泼尼龙联合阿奇霉素治疗小儿难治性支原体肺炎具有较好的临床疗效,并且安全性较高。

Objective:To analyze the efficacy and safety of methylprednisolone combined with azithromycin in treatment of children with refractory mycoplasma pneumonia.Methods:98children with refractory mycoplasma pneumonia were selected.They were divided into the two groups on average.Children in the control group were treated with azithromycin,and the study group was treated with azithromycin combined with methylprednisolone.The efficacy and safety of the two groups were compared.Results:The total effective rate of children in the study group was95.92%,higher than83.67%in the control group(P<0.05).The temperature recovery time(6.9±1.5)d in the study group was significantly lower than that in the control group(10.7±2.2)d(P<0.05).Conclusion:Methylprednisolone combined with azithromycin in treatment of children with refractory mycoplasma pneumonia has good clinical efficacy and high safety.