抗抑郁药联合α受体阻滞剂治疗慢性前列腺炎的临床疗效分析

Clinical efficacy analysis of antidepressant combined with α-receptor blocker in the treatment of chronic prostatitis

目的探讨抗抑郁药联合α受体阻滞剂治疗慢性前列腺炎的临床疗效。方法 100例慢性前列腺炎患者,随机分为试验组和对照组,各50例。对照组患者采用α受体阻滞剂联合维生素C治疗,试验组患者采用抗抑郁药联合α受体阻滞剂进行治疗。比较两组患者慢性前列腺炎症状评分表(NIH-CPSI)总体评分、抑郁自评量表(SDS)评分变化情况。结果两组患者治疗后NIH-CPSI总体评分、SDS评分均低于本组治疗前,差异有统计学意义(P<0.05);治疗后,试验组患者NIH-CPSI总体评分为(14.66±1.28)分、SDS评分为(40.16±0.56)分,均低于对照组的(19.09±3.38)、(53.89±0.33)分,差异均具有统计学意义(P<0.05)。结论抗抑郁药联合α受体阻滞剂治疗慢性前列腺炎临床效果显著,值得在临床推广。

Objective To discuss the clinical efficacy of antidepressant combined withα-receptor blocker in the treatment of chronic prostatitis.Methods A total of100chronic prostatitis patients were randomly divided into experimental group and control group,with50cases in each group.The control group was treated withα-receptor blocker and vitamin C,and the experimental group was treated with antidepressant andα-receptor blocker.Comparison were made on National Institutes of Health chronic prostatitis symptom index(NIH-CPSI)total score and self-rating depression scale(SDS)score changes in two groups.Results Both groups had lower NIH-CPSI total score and SDS score after treatment than before treatment,and the difference had statistical significance(P<0.05).After treatment,the experimental group had NIH-CPSI total score as(14.66±1.28)points and SDS score as(40.16±0.56)points,which were all lower than(19.09±3.38)and(53.89±0.33)points in the control group,and their difference had statistical significance(P<0.05).Conclusion Combination of antidepressant andα-receptor blocker shows remarkable clinical effect in treating chronic prostatitis,and it is worthy of clinical promotion.