痰热清注射液治疗老年呼吸机相关性肺炎患者的疗效分析

Efficacy analysis of Tanreqing injection in the treatment of senile patients with ventilator associated pneumonia

目的探讨痰热清注射液治疗老年呼吸机相关性肺炎(VAP)患者的临床疗效。方法 84例老年VAP患者,按随机数字表分为观察组与对照组,各42例。对照组患者常规给予抗感染对症支持治疗,观察组患者在抗感染对症支持治疗基础上应用痰热清注射液治疗,分析两组患者治疗1周后血清降钙素原(PCT)、临床肺部感染评分(CPIS)的变化及3个月后的复发率。结果治疗1周后,观察组患者PCT水平、CPIS评分明显低于对照组,差异有统计学意义(P<0.05)。治疗3个月后,观察组复发率为9.52%,明显低于对照组的26.19%,差异有统计学意义(P<0.05)。结论老年VAP患者同时应用抗菌药物结合痰热清注射液临床疗效更好,能降低复发率。

Objective To investigate the clinical efficacy of Tanreqing injection in the treatment of senile patients with ventilator associated pneumonia(VAP).Methods A total of84senile VAP patients were divided by random number table into observation group and control group,with42cases in each group.The control group received anti infective symptomatic supportive treatment,and the observation group also received Tanreqing injection.Analysis were made on serum procalcitonin(PCT),clinical pulmonary infection score(CPIS)changes after1week of treatment and recurrence rate after3months in two groups.Results After1week of treatment,the observation group had obviously lower PCT and CPIS score than the control group,and the difference had statistical significance(P<0.05).After3months of treatment,the observation group had obviously lowerrecurrence rate as9.52%than26.19%in the control group,and the difference had statistical significance(P<0.05).Conclusion Application of antimicrobials and Tanreqing injection shows good clinical efficacy for senile VAP patients,and it can reduce the recurrence rate.