盐酸洛哌丁胺胶囊治疗婴幼儿腹泻病临床观察

The Clinical Observation of Infant Dysentery Treated by Loperamide Hydrochlo-ride Capsules

目的:观察盐酸洛哌丁胺胶囊治疗婴幼儿腹泻病临床疗效。方法:选取泰和县妇幼保健院近年收治婴幼儿腹泻患儿98例,随机分为两组,对照组及观察组,各49例,对照组患儿给予蒙脱石散结合双歧杆菌四联活菌片进行治疗,观察组患儿给予蒙脱石散联合盐酸洛哌丁胺胶囊进行治疗,观察两组患儿治疗后临床总有效率及用药安全性。结果:观察组患儿治疗后临床症状好转时间与对照组比较无明显差异(P>0.05);观察组治疗总有效率(85.17%)略低于对照组(91.84%),差异无统计学意义(P>0.05);观察组各不良反应发生率与对照组相比,差异无统计学意义(P>0.05)。结论:盐酸洛哌丁胺胶囊应用于婴幼儿腹泻治疗中,临床疗效显著,使用安全性好,临床上可考虑使用。

Objective:To observe the clinical effect of infant dysentery treated by the Loperamide hydrochlo-ride capsules.Methods:98cases ofinfants with diarrhea at our hospital for treatment were randomly divided into two groups,the control group and the treatment group,with49casesin each.The control group was given the montmorillonite powder combines bifidobaeterium tetravaccine table for treatment,the treatment groupwas given the montmorillonite powder combines the loperamide hydrochlo-ride capsules for treatment,the clinical total efficacy rates after treatmentand drug safety of two groups were observed.Results:The improvement time of clinical symptoms after treatment in the treatment group showedno difference from the control group(P>0.05).The total treatment effective rate(85.17%)of the treatment group was slightly lower than the controlgroup(91.84%),but there was no statistical significance(P>0.05).Compared with the control group,the incidence of adverse reactions in theobservation group was not significant(P>0.05).Conclusion:The effect of loperamide hydrochlo-ride capsules for the treatment of infant dysenterywas obvious,and it has better security.