脂蛋白(a)及胆红素检验对冠心病的诊断价值研究

Diagnostic value of lipoprotein(a) and bilirubin in coronary heart disease

目的:探讨脂蛋白(a)及胆红素检验对冠心病的诊断价值。方法:收治冠心病患者120例作为观察组,选择健康体检者120例作为对照组,分别测定脂蛋白(a)及胆红素,比较检测结果。结果:观察组总胆红素明显低于对照组(P<0.05),两组直接胆红素及间接胆红素差异无统计学意义(P>0.05);观察组脂蛋白(a)明显高于对照组(P<0.05)。结论:脂蛋白(a)及胆红素与冠心病的发病关系密切,冠心病患者脂蛋白(a)明显升高,而胆红素明显降低,可作为快速诊断冠心病的指标,且具有积极的临床意义。

Objective:To explore the diagnostic value of lipoprotein(a)and bilirubin in coronary heart disease.Methods:120patients with coronary heart disease were selected as the observation group,and120healthy subjects were chosen as the controlgroup.Whey were given lipoprotein(a)and bilirubin determination.We compared the results of the test.Results:The total bilirubinin the observation group was significantly lower than the control group(P<0.05),and there was no significant difference betweengroups of direct bilirubin and indirect bilirubin(P>0.05).The lipoprotein(a)in the observation group was significantly higher thanthat in the control group(P<0.05).Conclusion:Lipoprotein(a)and bilirubin were closely related to the pathogenesis of coronaryheart disease.In patients with coronary heart disease,lipoprotein(a)levels were markedly elevated,while bilirubin levels weremarkedly lower.They can be used as a rapid diagnostic method for coronary artery disease,and had positive clinical significance.