专项整治活动前后抗菌药物应用及细菌耐药性分析

Analysis of utilization of antibacterials and bacterial drug resistance before and after special rectification

目的:分析专项整治活动前后我院抗菌药物使用情况及致病菌的耐药性变迁,为临床合理用药提供参考。方法 :对我院2011–2015年抗菌药物使用率、使用强度、用药频度、销售金额及细菌耐药等情况进行分析。结果:专项整治活动后,我院抗菌药物使用率由70.59%下降为38.62%;抗菌药物药占比由14.97%下降至6.27%;使用强度由73.04 DDD下降为26.89DDD·100人^(-1)·d^(-1),微生物送检率由33.50%上升至63.87%,抗菌药物使用率、使用强度、微生物送检率均达到文件规定的标准。结论:专项整治活动促进了我院抗菌药物的规范管理和合理使用,临床医师更加重视药敏试验对感染性疾病治疗的指导意义。

Objective:To analyze the clinical application of antibacterials and the bacterial drug resistance before andafter carrying out special rectification,so as to provide reference for rational use of antibacterials.Methods:The utilization rate ofantibacterials,density of use of antibacterials,frequency of medication,consumption sum,bacterial drug resistance in our hospitalfrom2011to2015were analyzed statistically.Results:After carrying out special rectification,the utilization rate of antibacterialsdropped from70.59%to38.62%,the proportion of antibacterials cost in drug expense decreased from14.97%to6.27%,the usedensity decreased from73.04to26.89DDD,the submission rate of microorganism increased from33.5%to63.87%.The utilizationrate of antibacterials,the density of use of antibacterials and the submission rate of microorganism reached the provisions of specialrectification.Conclusion:The special rectification for antibacterial agents can promote the standard management and reasonableapplication of antibacterials,physicians should attach more importance to the significance of drug sensitivity test in the treatment ofinfectious diseases.