中国人群无偿献血参与率及其影响因素的Meta分析

Meta-Analysis of The Determinants and Prevalence of Recruitment in Blood Donors among Chinese Population

目的对中国人群无偿献血参与率及其影响因素进行系统综述和Meta分析,为我国无偿献血招募策略的制定提供理论依据。方法检索2007年1月至2016年11月公开发表在中国生物医学文献数据库、中国知网、Pub Med的关于无偿献血行为及其影响因素的观察性研究。制定纳入和排除标准,对符合纳入标准的文献进行质量评价,利用R3.3.2软件的随机效应模型或固定效应模型计算无偿献血参与率及95%可信区间、相关影响因素的合并比值比及其95%可信区间,并按照调查对象、文献质量对纳入研究进行亚组分析,采用Egger回归法对发表偏倚进行分析。结果纳入文献29篇,有效样本含量35 759人;无偿献血参与率为30.0%,95%可信区间26.0%~34.0%;性别为男性(合并比值比1.47,95%可信区间1.13~1.91)、亲友有献血经历(合并比值比2.04,95%可信区间1.30~3.19)、主观规范(合并比值比2.09,95%可信区间1.43~3.04)、献血知识(合并比值比2.50,95%可信区间1.90~3.28)、献血态度(合并比值比2.32,95%可信区间1.59~3.40)是无偿献血行为的促进因素。结论未来无偿献血的招募策略应重视对女性献血者的招募、促进街头献血向团体献血转移、加强固定献血队伍的建立,普及献血者健康征询知识和用血政策等。

Objective To review and analyze the determinants and prevalence of recruitment in blood donors among Chinese population,and to provide scientific evidence for the recruitment of blood donors.Methods The published papers of observational studies on the determinants and prevalence of recruitment in blood donors from January2007to November2016were collected from Chinese BioMedical Literature Base(CBM),Chinese National Knowledge Infrastructure(CNKI),PubMed.The papers which met the inclusion criteria were evaluated.The pooled recruitment rate and95%confidence interval(CI)as well as OR and its95%CI for the determinants of recruitment in blood donors were calculated with R software version of3.3.2.Subgroup analysis were conducted based on the different population and the quality of literature.Egger was used to explore the publication bias.Results A total of29papers were selected,involving35759subjects.The results showed that the recruitment rate of the blood donors was30.0%(95%CI26.0%~34.0%);and male(OR=1.47,95%CI1.13~1.91),blood donor experience of relevant(OR=2.04,95%CI1.30~3.19),subjective norms(OR=2.09,95%CI1.43~3.04),with blood donor knowledge(OR=2.50,95%CI1.90~3.28)and positive attitudes toward blood donation(OR=2.32,95%CI1.59~3.40)were the promotion factors for blood donation.Conclusion The strategies of the blood donor recruitment should be focused on the female blood donor,and blood donor population transferred from street blood donor to group blood donor,and enhanced the fixed blood donor team,and promoted health literacy of the blood donor and explained the policy of blood use.