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p16INK4A、p53联合Ki-67对宫颈病变的检测价值

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摘要 目的探讨p16INK4A、p53联合Ki-67对宫颈病变的检测价值。方法取我院病理科2014年1月至2017年1月宫颈病变的患者,共计100例,取得病理组织蜡块,共100块。选择我院同期宫颈活检为慢性宫颈炎的患者为对照组,共100例。以病理结果为金标准,分析(1)研究组和对照组p16INK4A、p53及Ki-67阳性表达率。(2)不同病理组织p16INK4A、p53、Ki-67阳性表达率。结果 (1)研究组和对照组p16INK4A、p53联合Ki-67阳性表达率比较有差异(P<0.05)。(2)不同病理组织p16INK4A、p53、Ki-67阳性表达率存在差异。结论测定p16INK4A、p53、Ki-67的表达水平,有助于宫颈病变的检测。
作者 郭静
出处 《中国医药指南》 2017年第23期59-60,共2页 Guide of China Medicine
关键词 P16INK4A P53 KI-67 ER
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