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地西他滨联合CAG方案治疗骨髓增生异常综合征和急性髓系白血病的临床观察 被引量:7

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摘要 目的探讨地西他滨联合CAG方案治疗骨髓增生异常综合征(MDS)和急性髓系白血病的临床疗效。方法 42例骨髓增生异常综合征和急性髓系白血病患者,根据治疗方式不同分为对照组和试验组,各21例。对照组予以地西他滨展开治疗,试验组予以地西他滨协同CAG方案开展治疗,对比两组患者治疗效果。结果回访1~3年,对照组生存时长为(17.37±1.29)个月,有15例患者生存,总生存率为71.43%;试验组生存时长为(18.99±1.28)个月;有20例患者生存,总生存率为95.24%;试验组生存时长及总生存率均优于对照组,差异有统计学意义(P<0.05)。试验组不良反应发生率低于对照组,差异有统计学意义(P<0.05)。治疗后,对照组社会功能评分为(77.99±12.76)分,心理功能评分为(78.25±13.91)分,身体功能评分为(79.32±15.64)分;试验组社会功能评分为(92.26±21.41)分,心理功能评分为(95.73±21.12)分,身体功能评分为(94.12±24.85)分;试验组各项生活质量评分均高于对照组,差异有统计学意义(P<0.05)。结论地西他滨治疗骨髓增生异常综合征和急性髓系白血病患者具备较优的成效,值得大力推行及使用。
出处 《中国现代药物应用》 2017年第17期130-131,共2页 Chinese Journal of Modern Drug Application
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