卡前列素氨丁三醇注射液治疗宫缩乏力性产后出血疗效及安全性的临床观察

Observation on the efficacy and safety of carboprost tromethamine injection in the treatment of postpartum hemorrhage due to uterine atony

目的:探讨宫缩乏力性产后出血患者通过卡前列素氨丁三醇(欣母沛)进行治疗的效果及安全性。方法:收治产妇136例,分两组。对照组采用常规治疗,观察组在此基础上使用欣母沛治疗,对比患者产后出血量、凝血功能变化及不良反应。结果:观察组各时间段出血量显著少于对照组(P<0.05);观察组不良反应率显著低于对照组(P<0.05)。结论:欣母沛治疗宫缩乏力性产后出血患者,临床效果显著,不良反应率低。

Objective:To observe the efficacy and safety of carboprost tromethamine injection(hemabate)in the treatment of postpartum hemorrhage due to uterine atony.Methods:136cases of parturient women were selected,they were divided into the two groups,the control group was treated with conventional therapy,and the observation group was treated with hemabate,the changes of postpartum hemorrhage volume,blood coagulation function and adverse reactions were compared.Results:The amount of bleeding in observation group was lower than that in the control group(P<0.05).The adverse reaction rate of the observation group was significantly lower than that of the control group(P<0.05).Conclusion:The clinical effect of hemabate in the treatment of postpartum hemorrhage due to uterine atony is remarkable,and the rate of adverse reactions is low.