盐酸米诺环素与甲硝唑药膜在成人牙周炎临床治疗中的应用效果对比分析

Clinical effect of minocycline hydrochloride and metronidazole membrane in the treatment of adult periodontitis

目的:探讨盐酸米诺环素与甲硝唑药膜治疗成人牙周炎的临床效果。方法:收治成人牙周炎患者130例,随机分为对照组和观察组。观察组采用盐酸米诺环素治疗,对照组采用甲硝唑药膜治疗,比较两组治疗效果。结果:观察组临床有效率明显高于对照组(P<0.05)。治疗后,观察组牙菌斑指数(PLI)、牙龈指数(GI)、牙周附着指数(AL)、牙齿松动度(TM)、牙龈出血指数(SBI)和不良反应发生率明显低于对照组(P<0.05)。结论:盐酸米诺环素在成人牙周炎临床治疗中疗效更佳。

Objective:To explore the clinical effect of minocycline hydrochloride and metronidazole membrane in the treatment of adult periodontitis.Methods:130patients with adult periodontitis were selected.They were randomly divided into the control group and the observation group.The observation group was treated with minocycline hydrochloride,and the control group was treated with metronidazole membrane.We compared the therapeutic effect of two groups.Results:In the observation group,the clinical effective rate was significantly higher than that of the control group(P<0.05).After treatment,in the observation group,the plaque index(PLI),gingival index(GI),periodontal attachment index(AL),tooth mobility(TM),gingival bleeding index(SBI)and the incidence of adverse reactions were significantly lower than the control group(P<0.05).Conclusion:Minocycline hydrochloride was better in the treatment of adult periodontitis.